Cozy Bubble Up Biscuit Pizza Casserole
As the leaves change and a crisp autumn breeze sweeps through the air, there’s nothing more comforting than a cozy night in with a warm meal that brings everyone together. I fondly remember those evenings at my grandmother’s house, surrounded by loved ones, the aroma of homemade pizza wafting through the kitchen as we eagerly awaited dinner. Today, I’m excited to share my own version of that nostalgia with a fun twist: Bubble Up Biscuit Pizza Casserole! This dish has all the creamy, cheesy goodness of pizza but in a convenient, shareable casserole form that’s perfect for easy weeknight dinners or casual gatherings. This is one you’ll definitely want to pin for later!
Why You’ll Love This Recipe
- Quick Prep Time: This casserole comes together in no time, making it an ideal choice for busy weeknights.
- Family-Friendly Appeal: Kids and adults alike will love digging into a cheesy pizza casserole packed with their favorite toppings.
- Versatile Ingredients: You can customize this dish to fit any palate, choosing from a variety of toppings to suit your family’s tastes.
- One-Pan Wonder: Fewer dishes to wash means more time spent enjoying your cozy meal with loved ones.
- Perfect for Leftovers: If you happen to have any left, they store well and taste great reheated.
Ingredients You’ll Need for Bubble Up Biscuit Pizza Casserole
Gather these simple ingredients:
- 2 cans refrigerated buttermilk biscuits (*See Notes)
- 1 (15oz) jar pizza sauce
- 2 cups shredded mozzarella cheese
- Pizza toppings of choice (we love pepperoni & Italian sausage)
Let’s Make It Together
- Preheat your oven to 350° F and grease a 9×13 baking dish.
- Open both cans of biscuits and use a pizza cutter or knife to cut them into quarters or small bite-size pieces.
- Evenly place the dough onto the bottom of your prepared dish, trying to assemble them in a single layer. Place any that need to be slightly stacked near the edges of the pan where they bake the quickest.
- Use a spoon or small spatula to evenly spread the pizza sauce over top.
- Sprinkle the shredded mozzarella cheese over the sauce, followed by your chosen pizza toppings.
- Bake uncovered for 25-30 minutes, or until the dough is cooked through and the cheese begins to brown. Be sure to check the center first for doneness, as that part takes the longest to bake.
- Allow the casserole to cool for at least 5 minutes, then serve and enjoy!
Fun Ways to Customize It
- Veggie Lover’s Delight: Add slices of bell peppers, mushrooms, or onions for a zesty, colorful twist.
- Spicy Kick: Toss in some sliced jalapeños or crushed red pepper flakes for those who enjoy a little heat.
- Cheesy Extravaganza: Mix in varieties of cheese like cheddar or feta along with mozzarella for a richer flavor profile.
- Breakfast Pizza: Swap traditional toppings for scrambled eggs, turkey bacon, and a sprinkle of cheddar for a hearty brunch option.
Chef Emma’s Helpful Tips
- Make-Ahead: You can prepare this casserole in advance! Just cover it tightly and store it in the fridge overnight. Bake when you’re ready for a cozy meal.
- Ingredient Swaps: Don’t have buttermilk biscuits? Use regular refrigerated biscuits or even crescent rolls for a different texture.
- Cutting Tips: If you want uniform pieces, use kitchen scissors – they can be quicker than a pizza cutter for this task!
- Storage Suggestions: Leftovers can be stored in an airtight container in the refrigerator for up to 3 days. Reheat in the oven to maintain that glorious cheese gooeyness.
What’s Inside – Nutrition Breakdown
- Serving Size: 1 serving (1/12 of casserole)
- Calories: 300
- Carbohydrates: 22g
- Sugar: 3g
- Fat: 15g
- Protein: 12g
- Sodium: 600mg
Frequently Asked Questions
Can I make this ahead?
Absolutely! This casserole can be assembled in advance and stored in the refrigerator until you’re ready to bake it.
Can I use different ingredients?
Of course! Get creative with your toppings or use different sauces like Alfredo or barbecue for a unique flavor.
How do I store leftovers?
Store leftovers in an airtight container in the fridge for up to 3 days. Reheat in the oven to keep it delicious.
How long does it last?
This casserole tastes best within 3-4 days but is perfect for a quick meal during the week.
Wrapping It Up
This Bubble Up Biscuit Pizza Casserole captures the warmth and love of family gatherings while delivering deliciously cheesy goodness in a simple-to-make dish. It’s a comforting meal that invites everyone to come together, share stories, and savor every moment. Save this Bubble Up Biscuit Pizza Casserole to your Pinterest board so it’s ready when you need a cozy treat!

Cozy Bubble Up Biscuit Pizza Casserole
- Total Time: 45 minutes
- Yield: 12 servings 1x
- Diet: Vegetarian
Description
A comforting pizza casserole made with biscuit dough, pizza sauce, and your favorite toppings, perfect for family gatherings and weeknight dinners.
Ingredients
- 2 cans refrigerated buttermilk biscuits
- 1 (15 oz) jar pizza sauce
- 2 cups shredded mozzarella cheese
- Pizza toppings of choice (pepperoni, Italian sausage, etc.)
Instructions
- Preheat your oven to 350° F and grease a 9×13 baking dish.
- Open both cans of biscuits and cut them into quarters or small bite-size pieces.
- Evenly place the dough onto the bottom of your prepared dish in a single layer.
- Spread the pizza sauce evenly over the dough.
- Sprinkle the shredded mozzarella cheese over the sauce, followed by your chosen pizza toppings.
- Bake uncovered for 25-30 minutes, until the dough is cooked through and the cheese begins to brown.
- Allow the casserole to cool for at least 5 minutes before serving.
Notes
This casserole can be prepared in advance and stored in the refrigerator. Leftovers can be reheated in the oven.
- Prep Time: 15 minutes
- Cook Time: 30 minutes
- Category: Main Course
- Method: Baking
- Cuisine: Italian
Nutrition
- Serving Size: 1 serving
- Calories: 300
- Sugar: 3g
- Sodium: 600mg
- Fat: 15g
- Saturated Fat: 6g
- Unsaturated Fat: 7g
- Trans Fat: 0g
- Carbohydrates: 22g
- Fiber: 1g
- Protein: 12g
- Cholesterol: 0mg






